Detalhe da pesquisa
1.
Broadly effective metabolic and immune recovery with C5 inhibition in CHAPLE disease.
Nat Immunol
; 22(2): 128-139, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33398182
2.
Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH.
EMBO Rep
; 12(12): 1300-5, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22081141
3.
Immunization against proprotein convertase subtilisin-like/kexin type 9 lowers plasma LDL-cholesterol levels in mice.
J Lipid Res
; 53(8): 1654-61, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22611251
4.
The Association between Factor XI Deficiency and the Risk of Bleeding, Cardiovascular, and Venous Thromboembolic Events.
Thromb Haemost
; 122(5): 808-817, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-34555861
5.
A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo.
J Lipid Res
; 52(1): 78-86, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20959675
6.
A proprotein convertase subtilisin-like/kexin type 9 (PCSK9) C-terminal domain antibody antigen-binding fragment inhibits PCSK9 internalization and restores low density lipoprotein uptake.
J Biol Chem
; 285(17): 12882-91, 2010 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20172854
7.
FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases.
Proc Natl Acad Sci U S A
; 104(51): 20517-22, 2007 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-18077353
8.
Considerations for Soluble Protein Biomarker Blood Sample Matrix Selection.
AAPS J
; 22(2): 38, 2020 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31997095
9.
Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling.
Circulation
; 114(11): 1159-68, 2006 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-16952979
10.
Development and Fit-for-Purpose Validation of a Soluble Human Programmed Death-1 Protein Assay.
AAPS J
; 17(4): 976-87, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25924887
11.
2015 White Paper on recent issues in bioanalysis: focus on new technologies and biomarkers (Part 3--LBA, biomarkers and immunogenicity).
Bioanalysis
; 7(24): 3107-24, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26635247
12.
An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes.
Int J Biol Sci
; 8(3): 310-27, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22355267
13.
FoxO, autophagy, and cardiac remodeling.
J Cardiovasc Transl Res
; 3(4): 355-64, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20577843
14.
Characterization of the mouse adenylyl cyclase type VIII gene promoter: regulation by cAMP and CREB.
Eur J Neurosci
; 16(7): 1284-94, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12405989
15.
Regulation of RGS proteins by chronic morphine in rat locus coeruleus.
Eur J Neurosci
; 17(5): 971-80, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12653973